Technology: Illumina's Advanced Sequencing Platform

At tellmeGen we use advanced technology that allows us to obtain information from more than 750,000 genetic markers (SNPs). In addition, we customize this analysis with more than 10,000 additional SNPs to increase specificity and utility in both clinical practice and ancestry service analysis. To ensure the highest accuracy, we duplicate the probes analyzed, raising the reliability and reproducibility of the results to the highest quality standards in the industry. This allows us to provide detailed and reliable genetic information that meets the most demanding requirements.

1. Wide applications in research and clinical practice

   The variants included have been selected to allow us to obtain high imputation accuracy, specifically for variants with allelic frequency above 1%. In addition, specific variants have been included to allow us to achieve the best results related to both health and heritage.

2. Global content

   It includes a multiethnic spine of the entire genome, with the design of clinical research variants, quality control (QC) markers and the flexibility to add content.

3. High-performance workflow

   Supports high throughput processing of thousands of samples per week for population-scale studies. At tellmeGen we apply the combination of genetic knowledge and computational power to significantly increase the number of variants analyzable with a DNA chip to tens of millions. This imputation analysis allows us to be able to study variants that have been associated with diseases and that were not present in the initial 750,000 variants. This achieves our goal of estimating the genetic risk of each individual more accurately than ever before.

4. Robust, high-quality test

   The chip used by tellmeGen features a technology that allows a reproducibility > 99%.

Laboratory

Our reference laboratory is Eurofins Genomics Denmark, the only laboratory in Europe capable of processing the high number of samples that we receive and process on a monthly basis. It is a reference laboratory in Europe with the following certifications:

• ISO 17025: Accredited analytical excellence

• ISO 13485: Oligonucleotides according to medical devices standard

• GLP: The gold standard to conduct non-clinical safety studies

• GCP: Pharmacogenomic services for clinical studies

• cGMP: Products and testing according to pharma and biotech requirements